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Trypsin

/ˈtrɪpsɪn/noun

A pancreatic enzyme that breaks dietary protein into shorter chains in the small intestine.

The Greek roots

τρῖψις
trîpsis
rubbing, friction

Literally: rubbing substance

Follow a root:τρῖψις1 word

The story of the word

Wilhelm Kühne isolated it in 1876 and named it without explaining himself. The usual account ties the name to τρῖψις, rubbing, because he got the enzyme by grinding pancreas with glycerin; others prefer θρύπτειν, to break down, which fits what it does to protein. The argument has never been settled, and the year after, Kühne coined a second word that stuck even harder: enzyme.

How it travelled
Ancient Greek → German → English
First recorded
1876

Same family

trypsinogentribologydiatribe

In a sentence

Trypsin is secreted as an inert precursor so the pancreas does not digest itself.

Cell cultures are lifted off the flask with a few drops of trypsin.

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