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Monocyte

/ˈmɒnəsaɪt/noun

A large white blood cell with one unlobed nucleus, which matures into a macrophage in tissue.

The Greek roots

μόνος
mónos
single, alone
+
κύτος
kýtos
hollow vessel

Literally: single hollow vessel

The story of the word

The name counts lobes rather than cells. A monocyte carries one unsegmented nucleus, which separates it at a glance from the neutrophils with their pinched and beaded ones, and pathologists needed that distinction long before anyone knew what either cell was for. Leave the bloodstream and the monocyte changes name as well as job: settled in tissue it becomes a macrophage, so one cell answers to two words depending on where it is standing.

How it travelled
Ancient Greek → scientific coinage → English
First recorded
early 20th century

Same family

monopolymonolithmonkerythrocyte

In a sentence

A high monocyte count sent them looking for a chronic infection.

Monocytes are the cells that turn into the tissue's cleanup crew.

Built on the same root

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