Skip to content
Medicine & BodyGreekEnglish

Histamine

/ˈhɪstəmiːn/noun

A compound released by mast cells in allergic reactions, causing itching, swelling and dilated blood vessels.

The Greek roots

ἱστός
histós
web, loom, tissue

Literally: tissue amine

Follow a root:ἱστός3 words

The story of the word

Henry Dale and Patrick Laidlaw isolated it around 1910 and named it for where it comes from, tissue, plus its chemical class, amine. ἱστός meant the upright loom and the web woven on it, and anatomists borrowed the weaving image for the fabric of the body, which is also why the study of it is histology. Antihistamines work by blocking the receptors rather than removing the histamine.

How it travelled
Ancient Greek → scientific coinage → English
First recorded
1910s

Same family

histologyhistogramantihistamine

In a sentence

Pollen sets off a flood of histamine, and the sneezing follows.

Built on the same root

More from Medicine & Body