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Dystrophy

/ˈdɪstrəfi/noun

The progressive wasting of a tissue, most often used of the inherited muscle diseases.

The Greek roots

δυσ-
dys-
bad, faulty
+
τροφή
trophḗ
nourishment, feeding

Literally: faulty nourishment

The story of the word

The name preserves a nineteenth-century guess that the muscles were wasting because they were being badly fed. Duchenne described the commonest form in the 1860s; the real cause turned out to be a missing structural protein, which was found in 1987 and named dystrophin after the disease rather than the other way round. δυσ- is the exact opposite of εὖ, which is why dysentery and euphoria sit at either end of the same shelf.

How it travelled
Ancient Greek → scientific coinage → English
First recorded
19th century

Same family

atrophyhypertrophydysenterytrophic

In a sentence

Her brother has the same dystrophy, diagnosed at four.

Built on the same root

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